Ovacome :Ovarian Cancer News

Ovarian Cancer News

'Genetic screening can cut deaths from ovarian cancer'

May 2010

It is now possible to predict our genetic predisposition to many conditions. A recent Harvard study examined gene mutations in breast cancer cells that were responsible for a lack of response to anthracycline chemotherapy. This could pave the way for tailor-made treatments for cancer sufferers.

It is less clear, however, whether we should advocate diagnostic genetic testing in healthy people, unless they are at high risk. The National Institute for Clinical Excellence (Nice) has recommended genetic testing for conditions such as breast cancer, where the lifetime risk is one in three or higher, based on family history of breast and ovarian cancers. On average, the lifetime risk is one in nine.

Can you help with research on cancer related fatigue?

March 2010

Researchers in Trinity College Dublin are investigating the causes of cancer fatigue and the factors that contribute to the development of chronic fatigue in some cancer patients. The study is funded by the Irish Cancer Society and the IRCSET 'Embark Initiative'.

Who can participate?
Anyone who (a) has been treated for cancer or is currently being treated for cancer and (b) is experiencing fatigue.

What does participation involve?
Participation involves filling in a number of questionnaires about your fatigue, the factors you believe contribute to your fatigue, and the coping strategies you use to manage this symptom.

How can I participate?
If you would like to participate please complete this online questionnaire: http://www.surveymonkey.com/s/CancerFatigueStudy

If you would prefer to complete the questionnaire in hard copy or if you would like further information, please contact the researcher: Maria Pertl (Phone: 01 896 3083 / E-mail: pertlm@tcd.ie).

Ovacome member Emily McArthur: Ovarian cancer didn't stop me having a baby

March 2010

I may have had cancer - twice - but I'd like to think I haven't let it control my life. It's just that I've ended up following a different path from the one I anticipated. While I've got to 30 the hard way I'm now healthy.

Most incredibly of all, I have my baby daughter Molly, who is now nine months old. I'm so lucky. Having a baby after ovarian cancer is rare and especially so after having it twice. Molly did more than just make me a mum she also stopped people looking at me as simply a cancer patient.

'We'll never forget you'

February 2010

Deborah Garrett's death from ovarian cancer at just 38 left
her family shattered - here they remember her brave fight in a special issue of Fabulous magazine focussing on gynaecological cancers.

Ovarian cancer treatment on trial

January 2010

A breakthrough in the treatment of ovarian cancer is this week being trialled in Britain. It could save the lives of thousands of women, medical researchers believe.

A joint British-Canadian trial of the new technique, known as intraperitoneal chemotherapy, will be launched at Barts and The London School of Medicine and Dentistry.

'I didn't want to lose my hair after chemotherapy'

January 2010

Melanie Rowland is very proud of her thick white hair.She did not realise just how important it was to her until she risked losing it all, during chemotherapy.

But thanks to a charity donation of a scalp cooler the 61-year-old from Surrey was able to keep the vast majority of her hair. The machines work by lowering the temperature of the head and scalp by a few degrees before, during and after chemotherapy.

GP's surgeries to get software that spots early cancer symptoms and calculates risk

January 2010

There are more than 200 forms of cancer, and many of their symptoms are the same as for a range of other, often less serious, conditions. Computers could help doctors get it right more often when deciding whether to investigate a patient further, discharge them or refer them to hospital.

"This is helping GPs because none of us can retain this sort of information [about cancer symptoms] and having to retain it for bowel cancer, lung cancer and ovarian cancer, as well as for heart disease, it would take a remarkable human brain to be able to do that, so why not get computers to support it?" said Professor Mike Richards, the government's cancer tsar.

What it feels like to survive ovarian cancer

November 2009

When Ovacome member Jennifer Smith's tummy swelled up, she put it down to overeating. It was the only sign she had a life-threatening disease.

""I was just 40 when I was diagnosed with ovarian cancer. That's pretty unusual - only 15% of cases occur in women below the age of 50. It's one of those diseases that's completely unsexy. It lacks the trendy factor: we don't have a poster girl like Kylie Minogue. Ask a bunch of women what to look for with breast cancer and most will know at least a little. Ask them about ovarian cancer and the majority won't even have heard of it, let alone know what the symptoms are. I was one of those. "

Speedier tests for ovarian cancer planned

September 2009

GPs in England are to get speedier access to diagnostic tests to help spot less clear-cut cancer cases, Prime Minister Gordon Brown will pledge.

It will initially be targeted at lung, colorectal and ovarian cancers, which account for more than a third of cancer deaths and where late diagnosis is a particular problem.

Ovacome comments on the OvPlex ovarian cancer detection test

September 2009

Louise Bayne, CEO of Ovacome:

"Ovacome welcomes this latest development, however we don't anticipate that this test will be available on the NHS for some time. If you have any questions or concerns about screening, please contact our nurses on 0845 371 0554."

For more information, visit the OvPlex website.

On more weapon in the fight against ovarian cancer

August 2009

A genetic link to the disease, which often lies hidden until it's so advanced that it's difficult to treat, was revealed earlier this month.

The study involved more than 4,000 UK women and collaboration between the Cancer Research UK Genetic Epidemiology Unit at the University of Cambridge and University College, London.

The first glimmer of hope of more tailored screening?

August 2009

A study published in Nature Genetics this week reported on a new development in ovarian cancer genetics. They have discovered a genetic variation, known as a Single Nucleotide Polymorphism ('SNP' - known as a 'snip') which can increase the risk of ovarian cancer. The scientists based at the Cancer Research UK Genetic Epidemiology Unit, at the University of Cambridge and University College London, have spent eight years looking at the DNA of thousands of women with and without ovarian cancer. The area of risk DNA otherwise known as a low penetrance gene is on chromosome 9. Louise Bayne CEO of Ovacome said: "This is the first of the low penetrance ovarian cancer genes - which slightly increase the risk of ovarian cancer - to be identified and Ovacome welcomes this exciting advance."

What is a low penetrance gene?

Dr James Mackay, Consultant Clinical Genetic Oncologist, explains that low penetrance genes slightly increase the risk of ovarian cancer, whereas high penetrance genes such as BRCA1 and BRCA2 increase the risk much more. If you imagine a room with 1000 women in it, and imagine they all had totally normal genes, over their lifetimes, 10 of the women in the room would get ovarian cancer. Now if you imagine that all the 1000 women had this new genetic 'SNP', then over a lifetime 14 of the women would get ovarian cancer. If you imagine that they all had a BRCA gene mutation, 400 of them would get ovarian cancer. So you can see that although this does increase the risk of ovarian cancer a little, it is a small increase compared to some of the major genetic detections we already know about. The really important thing about this study is that, as more low penetrance ovarian cancer genes are identified, a more tailored approach to screening could be provided.

"I was only 31 when I got ovarian cancer -- so I urge all women to get checked out"

July 2009

The Irish Cancer Society (ICS) is calling on the Government to urgently set up risk-assessment clinics for ovarian cancer in strategic locations around the country.

Ovarian cancer signs 'confusion'

June 2009

There is "widespread confusion" amongst doctors and women about ovarian cancer, a new report has said.

A spokesman for the Royal College of GPs said it was "extraordinarily difficult" to diagnose ovarian cancer at an early stage.